The purpose of this paper is to review a series of measures taken by China and South Korea in response to the COVID-19 epidemic and get some lessons from the cases of two countries. As of October 7, 2020, the COVID-19 is still raging in the world. China and South Korea have basically controlled the further deterioration of the epidemic, but the loss to the socio-economic and people’s lives and safety of the two countries is irreversible. This has once again knocked the crisis & emergency management work of the two governments, and at the same time, this epidemic was a major test for the perfection of emergency management systems in countries around the world. When a public crisis occurs, how to respond quickly and effectively, and build a rapid and effective emergency management system to ensure the steady development of the social economy, respect and maintain the safety of people's lives, is a problem that government departments and managers must think about. Major results of this research are as follows; ① Early Identification of Dangers and Rapid Response, ② Rapid and Complete Quarantine Measures, ③ Tracking the Path of the Diagnosed Person, ④ Citizen Participation to Perform Social Responsibility.